Serotonin syndrome: a spectrum of toxicity
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چکیده
منابع مشابه
Toxicity of a serotonin-derived neuromelanin.
Postoperative Cognitive Dysfunction (POCD) is associated with increased mortality in the elderly and may occur from lipid peroxidation in aging. We previously showed that sevoflurane sequesters acrolein, which promotes the formation of a novel species of a putative neuromelanin. The current study examined the properties of this serotonin-derived melanoid (SDM). The interaction of SDM with unila...
متن کاملSerotonin syndrome.
Serotonin syndrome is a potentially serious clinical condition. In this article, the authors put serotonin syndrome into historical context, discuss its pathophysiology, review in detail its clinical presentations, diagnostic criteria, differential diagnosis and treatment. Special attention is given to drugs that most often cause serotonin syndrome, and the gene polymorphisms involved in the me...
متن کاملSerotonin syndrome.
BMJ | 1 MARCH 2014 | VOLUME 348 33 NSW Poisons Information Centre, Sydney, Australia Sydney Medical School, University of Sydney, NSW 2006 Department of Clinical Toxicology, Royal Prince Alfred Hospital, Sydney School of Medicine and Public Health, University of Newcastle, Newcastle, Australia Correspondence to: N A Buckley [email protected] Cite this as: BMJ 2014;348:g1626 doi: 10.1136/bmj...
متن کاملSerotonin syndrome.
BACKGROUND Serotonin syndrome is a potentially life-threatening syndrome that is precipitated by the use of serotonergic drugs and overactivation of both the peripheral and central postsynaptic 5HT-1A and, most notably, 5HT-2A receptors. This syndrome consists of a combination of mental status changes, neuromuscular hyperactivity, and autonomic hyperactivity. Serotonin syndrome can occur via th...
متن کاملSerotonin syndrome: a brief review.
A 50-year-old man was admitted to hospital with hyperhidro-sis, nausea, vomiting and diarrhea. He had been taking fluoxe-tine (120 mg/d), meprobamate (400 mg/d) and aceprometazine (13.55 mg/d). The dose of fluoxetine had just been increased. The patient was agitated and had insomnia and hyperreflexia, but there were no focal neurological findings. His blood pressure was 155/80 mm Hg, his heart ...
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ژورنال
عنوان ژورنال: BJPsych Advances
سال: 2015
ISSN: 2056-4678,2056-4686
DOI: 10.1192/apt.bp.114.013037